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Table 3 Summary of results from 13 included studies

From: Optimal sampling designs for estimation of Plasmodium falciparum clearance rates in patients treated with artemisinin derivatives

Country

Proportion of patients

Median HL; range; IQR

CV (%)

Std dev log(HL)

Prop NZ tlag

Median NZ tlag

Prop with tail

Thailand1

46% (1571/3391)

3.05; 0.889-12.9; 2.37-4.24

46.4

0.438

26.4% (n = 415)

6

42.1% (n = 662)

Thailand2

82% (33/40)

2.87; 1.48-7.54; 2.11-3.77

46.8

0.421

18.2% (n = 6)

4.05

54.5% (n = 18)

Thailand3

88% (70/80)

3.26; 0.964-9.09; 2.36-4.42

50.4

0.49

24.3% (n = 17)

6

41.4% (n = 29)

Mali

99% (258/261)

1.87; 0.678-4.27; 1.57-2.34

30.0

0.296

58.1% (n = 150)

6

1.55% (n = 4)

Cambodia1

97% (57/59)

6.11; 2.53-9.5; 4.93-7.18

26.1

0.285

21.1% (n = 12)

12

45.6% (n = 26)

Cambodia2

94% (74/79)

5.79; 2.07-9.37; 4.85-7.32

31.1

0.359

24.3% (n = 18)

6.02

40.5% (n = 30)

Cambodia3

99% (78/79)

6.09; 1.71-11.2; 4.69-7.15

32.4

0.377

7.69% (n = 6)

6

14.1% (n = 11)

Cambodia4

100% (98/98)

6.5; 2.13-11.3; 5.14-7.73

29.2

0.329

6.12% (n = 6)

15

2.04% (n = 2)

Cambodia5

100% (30/30)

5.75; 2.66-10.5; 4.12-7.48

34.5

0.363

33.3% (n = 10)

15

13.3% (n = 4)

Cambodia6

78% (43/55)

2.62; 1.13-4.43; 2.31-3

25.9

0.278

6.98% (n = 3)

6

27.9% (n = 12)

Cambodia7

98% (140/143)

7.03; 1.7-11.8; 5.6-8.11

31.6

0.397

6.43% (n = 9)

6

57.1% (n = 80)

Kenya

93% (159/171)

2.49; 0.956-5.19; 1.89-3.09

33.1

0.354

19.5% (n = 31)

6

0% (n = 0)

Vietnam

81% (135/166)

2.9; 1.02-10.2; 2.04-5.46

59.3

0.572

34.1% (n = 46)

6.23

40.7% (n = 55)

Total

59% (2746/4652)

3.13; 0.678-12.9; 2.29-5

53.8

0.519

26.5% (n = 729)

6 (6–6.25)

34% (n = 933)

  1. For each of the studies, country; proportion of total patients included; median HL (range; IQR); coefficient of variation (CV) as a percentage; standard deviation of log (HL); proportion of profiles with a non-zero tlag; the median tlag for the profiles with a non-zero tlag; and the proportion of profiles with a tail. The bottom row gives the corresponding values for the pooled dataset. IQR = interquartile range; NZ = non-zero; prop = proportion.