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Table 3 Summary of results from 13 included studies

From: Optimal sampling designs for estimation of Plasmodium falciparum clearance rates in patients treated with artemisinin derivatives

Country Proportion of patients Median HL; range; IQR CV (%) Std dev log(HL) Prop NZ tlag Median NZ tlag Prop with tail
Thailand1 46% (1571/3391) 3.05; 0.889-12.9; 2.37-4.24 46.4 0.438 26.4% (n = 415) 6 42.1% (n = 662)
Thailand2 82% (33/40) 2.87; 1.48-7.54; 2.11-3.77 46.8 0.421 18.2% (n = 6) 4.05 54.5% (n = 18)
Thailand3 88% (70/80) 3.26; 0.964-9.09; 2.36-4.42 50.4 0.49 24.3% (n = 17) 6 41.4% (n = 29)
Mali 99% (258/261) 1.87; 0.678-4.27; 1.57-2.34 30.0 0.296 58.1% (n = 150) 6 1.55% (n = 4)
Cambodia1 97% (57/59) 6.11; 2.53-9.5; 4.93-7.18 26.1 0.285 21.1% (n = 12) 12 45.6% (n = 26)
Cambodia2 94% (74/79) 5.79; 2.07-9.37; 4.85-7.32 31.1 0.359 24.3% (n = 18) 6.02 40.5% (n = 30)
Cambodia3 99% (78/79) 6.09; 1.71-11.2; 4.69-7.15 32.4 0.377 7.69% (n = 6) 6 14.1% (n = 11)
Cambodia4 100% (98/98) 6.5; 2.13-11.3; 5.14-7.73 29.2 0.329 6.12% (n = 6) 15 2.04% (n = 2)
Cambodia5 100% (30/30) 5.75; 2.66-10.5; 4.12-7.48 34.5 0.363 33.3% (n = 10) 15 13.3% (n = 4)
Cambodia6 78% (43/55) 2.62; 1.13-4.43; 2.31-3 25.9 0.278 6.98% (n = 3) 6 27.9% (n = 12)
Cambodia7 98% (140/143) 7.03; 1.7-11.8; 5.6-8.11 31.6 0.397 6.43% (n = 9) 6 57.1% (n = 80)
Kenya 93% (159/171) 2.49; 0.956-5.19; 1.89-3.09 33.1 0.354 19.5% (n = 31) 6 0% (n = 0)
Vietnam 81% (135/166) 2.9; 1.02-10.2; 2.04-5.46 59.3 0.572 34.1% (n = 46) 6.23 40.7% (n = 55)
Total 59% (2746/4652) 3.13; 0.678-12.9; 2.29-5 53.8 0.519 26.5% (n = 729) 6 (6–6.25) 34% (n = 933)
  1. For each of the studies, country; proportion of total patients included; median HL (range; IQR); coefficient of variation (CV) as a percentage; standard deviation of log (HL); proportion of profiles with a non-zero tlag; the median tlag for the profiles with a non-zero tlag; and the proportion of profiles with a tail. The bottom row gives the corresponding values for the pooled dataset. IQR = interquartile range; NZ = non-zero; prop = proportion.