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Table 2 Overview of relevant laboratory test results of donor

From: A case report of transfusion-transmitted Plasmodium malariae from an asymptomatic non-immune traveller

Collection date

Laboratory test

Result

Specimen

27 February 2007

Thrombocyte count

141 × 109/L

Fresh blood

22 May 2007

Thrombocyte count

94 × 109/L

Fresh blood

9 February 2011

Plasmodium species PCR *

Negative

Stored plasma

Malaria serology by ELISA *

Negative (0.36, cut off <1.0)

Stored plasma

Malaria serology by immunofluorescence assay (IFA) *

Positive (1:40, cut-off <1:40)

Stored plasma

7 June 2011

Plasmodium genus PCR

Positive for Plasmodium spp.

EDTA-blood

Malaria serology by immunofluorescence assay (IFA)

Positive (1:160, cut-off <1:40)

Serum

Plasmodium species PCR

Positive for P. malariae

EDTA-blood

17 August 2011

Thrombocyte count

126 × 109/L

Fresh blood

Thick blood smear, QBC, malaria antigen test

Negative

Fresh blood

8 November 2011

Thrombocyte count

128 × 109/L

Fresh blood

QBC, malaria antigen test, thin blood smear, malaria serology (ELISA)

Negative

Fresh blood

Thick blood smear

One structure suspected for P. malariae

Fresh blood

Plasmodium species PCR

Positive for P. malariae

Fresh blood

Plasmodium species PCR

Positive for P. malariae

Bone marrow biopsy

Leishmania spp. PCR

Negative

Bone marrow biopsy

26 November 2011

Thrombocyte count

144 × 109/L

Fresh blood

1 December 2011

Thrombocyte count

157 × 109/L

Fresh blood

12 July 2012

Thrombocyte count

139 × 109/L

Fresh blood

Thick and thin blood smears, QBC, malaria antigen test, malaria serology (ELISA), Plasmodium species PCR

Negative

Fresh blood

6 March 2013

Thrombocyte count

209 × 109/L

Fresh blood

 

Thick and thin blood smears, QBC, malaria antigen test, malaria serology (ELISA), Plasmodium species PCR

Negative

Fresh blood

  1. The tests were performed in the following laboratories: Diagnostic Services, Sanquin Blood Supply Foundation, Amsterdam (2007 and malaria serology by ELISA first half 2011); Dept. Medical Microbiology, University Medical Centre St Radboud, Nijmegen, and/or Dept. Parasitology, Leiden University Medical Centre, Leiden (first half 2011); the Harbour Hospital Laboratory, Dept. Medical Microbiology and Infectious Diseases and Clinical Chemistry, Erasmus University Medical Centre and Harbour Hospital, Rotterdam (from August 2011 onwards). Tests marked by an *indicate results of tests performed retrospectively in May to July 2011 on materials collected on 9 February 2011.