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Figure 5 | Malaria Journal

Figure 5

From: Identification of active Plasmodium falciparum calpain to establish screening system for Pf-calpain-based drug development

Figure 5

Comparison of the Pf -calpain model to the active and inactive forms of the typical calpain. A) Rat calpain 2 without Ca2+ ion (1U5I.pdb). B) Rat calpain 2 complexed with Ca2+ ions (1MDW.pdb). C) The homology model of Pf-calpain subdomain IIa. Catalytic triad residues are displayed in sticks and their residue numbers are marked. Figure is generated by the SYBYL v.8.1.1.

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