A clinicopathological correlation of the expression of the angiopoietin-Tie-2 receptor pathway in the brain of adults with Plasmodium falciparum malaria

Table 2 Comparison of prognostic value of plasma marker concentrations for fatal outcome

Marker	AUC (95%CI)	Compared to Ang-2	Compared to Ang-2/Ang-1 Ratio
Ang2	0.727 (0.600-0.854)
Ang2/Ang1 Ratio	0.662 (0.522-0.802)	0.82, 0.36
Creatinine	0.708 (0.575-0.840)	0.09, 0.77	0.22, 0.64
Lactate	0.666 (0.528-0.804)	0.4, 0.52	0.01, 0.93
TNF (n=32)	0.696 (0.528-0.863)	0, 1	0.57, 0.75

AUC = area under ROC curve, Data are x², P- value unless otherwise indicated. All X² and P-value are calculated from pairwise nonparametric comparison of areas under ROC curve.

ISSN: 1475-2875