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Table 3 Treatment responses on day 28

From: Artesunate-amodiaquine efficacy in Congolese children with acute uncomplicated falciparum malaria in Brazzaville

  Total Age Residence
   ≤ 5 yrs old > 5 yrs old Urban area Suburban area
Number of patients: N 197 96 101 125 72
PCR uncorrected responses on day 28 Withdrawn + Lost-to-follow-up, N (%) 15 (7.6) 10 (10.4) 5 (5) 11 (8.8) 4 (8.1)
Eligible; N (%) 182 (92.4) 86 (89.6) 96 (95) 114 (91.2) 68 (91.9)
Failure; N (%) 31 (17) 20 (23.3) 11 (11.5) 18 (15.8) 13 (19.1)
ETF; N (%) 1 (0.5) 0 1 (1) 1 (0.9) 0
LCF; N (%) 14 (7.7) 10 (11.2) 4 (4.2) 9 (7.9) 5 (7.4)
LPF; N (%) 16 (8.8) 10 (11.2) 6. (6.3) 8 (7) 8 (11.8)
ACPR; N (%) 151 (83) 66 (76.7) 85 (88.5) 96 (84.2) 55 (80.9)
PCR corrected responses on day 28 Withdrawn + Lost-to-follow-up + reinfection + not analyzed; N (%) 37 (18.8) 26 (27.1) 11 (10.9) 24 (19.2) 13 (18.1)
Eligible; N (%) 160 (81.2) 70 (72.9) 90 (89.1) 101 (80.8) 59 (81.9)
Failure; N (%) 9 (5.6) 4 (5.7) 5 (5.6) 5 (5) 4 (6.8)
ETF; N (%) 1 (0.6) 0 1 (1.1) 1 (1) 0
Recrudescence; N (%) 8 (5) 4 (5.7) 4 (4.5) 4 (4) 4 (6.8)
ACPR; N (%) 151 (94.4) 66 (94.3) 85 (94.4) 96 (95) 55 (93.2)
Recrudescence; N 8 4 4 4 4
  Reinfection; N 10 7 3 3 7
  1. N, Number; ACPR, adequate clinical and parasitological response; LPF, late parasitological failure; LCF, late clinical failure; ETF, early treatment failure.
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