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Table 3 Effect of drugs on Plasmodium falciparum growth using cultures grown at low and high parasitaemia

From: Magnetic isolation of Plasmodium falciparum schizonts iRBCs to generate a high parasitaemia and synchronized in vitro culture

IC50 (nM)
Drug P = 40% P = 5%
Atovaquone 1.00 ± 0.17 0.95 ± 0.14
Chloroquine 11.33 ± 3.48 16.30 ± 2.20
Artemisinin 40.75 ± 2.35 40.29 ± 6.05
Pyrimethamine 112.00 ± 53.62 117.59 ± 89.61