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Table 1 Subject characteristics and treatment outcomes

From: Two novel mutations of pfdhps K540T and I588F, affecting sulphadoxine-pyrimethamine-resistant response in uncomplicated falciparum malaria at Banjar district, South Kalimantan Province, Indonesia

Characteristics No of patients (n = 61)
Median age in years (range) 25 (14–55)
Male: Female 49: 12
Mean parasite density of D0 (per μl) (range) 2,835 (40–38,368)
Adequate clinical parasitogical response (%) 22 (36.1)
Parasitological failure* (%) 39 (63.9)
 Early treatment failure (ETF) 16 (26.2)
 Late parasitological failure (LPF) 23 (37.7)
Late clinical failure (%) 0  
Parasite clearance** (%): A) B)
 On D3 18 (29.5) 15 (24.6)
 On D7 22 (36.1) 20 (32.8)
 On D14 35 (57.4) 32 (52.5)
 On D21 40 (65.6) 38 (62.3)
 On D28 47 (77.0) 43 (70.5)
  1. *Parasitological failure is either early treatment failure or late parasitological failure cases. The actually detected parasites were few in number in many cases and it makes some cases difficult to determine whether ETF or LPF clearly.
  2. **Parasite clearance was determined by microscopy, when A) the cases that an asexual parasite was not detected even gametocytes were observed on the day after treatment; B) the cases that neither asexual nor sexual parasites were detected on the day after treatment. D0 = on the day of treatment.