Figure 2From: Assessment of the prophylactic activity and pharmacokinetic profile of oral tafenoquine compared to primaquine for inhibition of liver stage malaria infectionsRepresentative in vivo images (IVIS) of luminescence shown in the livers of live C57BL/6 albino mice at different time points after injection of 5 × 104sporozoites. Rainbow images show the relative levels of luminescence ranging from low (blue), to medium (green), to high (yellow/red). Luminescence levels (photons/sec) of livers in whole mice at 24, 48 and 72 hour time points following intragastric dosing daily for 3-consecutive-day on days -1, 0, 1, treated with tafenoquine (TQ) at a dose of 5 mg/kg (TQ, left) and vehicle control (VC, right) after sporozoite infection intravenously at day 0. Normally, P. berghei sporozoites reside in the mouse liver for 44–52 hours post-infection (n = 4).Back to article page