Skip to main content

Table 3 Relapse incidence rates for the modified Macdonald system

From: Geographical variation in Plasmodium vivax relapse

Ecological zone

Based on raw data, ML with 95% CI

Model-based, REML with 95% CI

1

357 (CI: 318–400)

455 (CI: 313–662)

2

217 (CI: 198–238)

259 (CI: 120–557)

3

419 (CI: 328–528)

1093 (CI: 535–2,233)

5 + 6

214 (CI: 186–245)

262 (CI: 82–839)

7

221 (CI: 191–255)

213 (CI: 95–477)

8

25 (CI: 24–26)

62 (CI: 33–116)

9 + 10

975 (CI: 811–1163)

836 (CI: 351–1,995)

11 + 4

138 (CI: 120–159)

134 (CI: 64–278)

12

1023 (CI: 981–1,067)

1224 (CI: 689–2,174)

  1. The numbers are presented as first relapses per 100,000 person days. The estimate based on raw data is obtained by dividing the number of relapses by follow-up time and using Ulm’s exact formula [73] for confidence intervals. The model-based estimates are calculated from the results obtained from meta-analysis performed by the R package metafor. ML refers to the maximum likelihood and REML to restricted maximum likelihood.