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Table 3 Diagnostic accuracy of Pf HRP2- compared to Pf -pLDH-detection

From: Accuracy of Pf HRP2 versus Pf-pLDH antigen detection by malaria rapid diagnostic tests in hospitalized children in a seasonal hyperendemic malaria transmission area in Burkina Faso

  Pf HRP2 Pf-pLDH p-value
RDT pos, n (%) 515 (74.2) 404 (54.2)  
SE (95% CI) 100.0 (94.7 - 100.0) 98.7 (93.5-99.9) 1.0
Sp (95% CI) 70.9 (67.4 - 70.9) 94.0 (90.6 - 94.8) < 0.001
PPV (95% CI) 69.4 (65.7 - 69.4) 91.6 (86.8 - 92.7) < 0.001
NPV (95% CI) 100.0 (95.1 - 100.0) 99.1 (95.5 - 100.0) 1.0
  1. N = number, NPV = negative predictive value, Pf HRP2 = P. falciparum Histidine-rich protein-2, Pf-pLDH = P. falciparum- specific parasite lactate dehydrogenase pos = positive, PPV = positive, predictive value SE = sensitivity, Sp = specificity.