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Table 1 RDT test performance by CHWs

From: Success or failure of critical steps in community case management of malaria with rapid diagnostic tests: a systematic review

Study Target population RDT type Reference standard (RS) RS positive* (%) Sensitivity (%) Specificity (%)
Ratsimbasoa[29] >2 months (history of) fever CareStart PCR 56.7% 61.8% 95%
Ratsimbasoa[29] >2 months (history of) fever CareStart Microscopy of thin and thick BS 37.2% 95.9% 87%
Chinkhumba[30] >5 years (history of) fever Bioline SD, First Response malaria, Paracheck PF Microscopy of thick BS (expert) 38.5% 95% 43%
Chinkhumba[30]** >5 years (history of) fever Bioline SD Microscopy of thick BS (expert). 41% 97% 39%
Chinkhumba[30]** >5 years (history of) fever First response malaria Microscopy of thick BS (expert). 40% 92% 42%
Ishengoma[28] All ages, care seeking Paracheck Pf, ParaHIT Microscopy of thick and thin BS. 20.8% 88.6% 88.2%
Ishengoma[28] < 5 years Paracheck Pf, ParaHIT Microscopy of thick and thin BS 19.7% 90.1% 93.6%
Ishengoma[28] ≥5 years Paracheck Pf, ParaHIT Microscopy of thick and thin BS 21% 88.3% 86.5%
Ishengoma[28] No fever patients Paracheck Pf, ParaHIT Microscopy of thick and thin BS 14.5% 84.7% 90.1%
Ishengoma[28] Fever patients Paracheck Pf, ParaHIT Microscopy of thick and thin BS 33.9% 92.2% 82.9%
Lemma[22]** >3 months suspected of malaria Paracheck Pf Microscopy of thick BS. 18.7% 88.7% 94.2%
Lemma[22]** >3 months suspected of malaria Parascreen Microscopy of thick BS. 18.7% 83.2% 95.1%
Mubi[24] >3 months (history of) fever. Paracheck Pf Microscopy of thick BS. 22.6% 85.3% 59.8%
Premji[31] Children <42 months Parasight TM-F test Microscopy of thin and thick BS. 66.6% 84% 81%
Tiono[14] Children 6–59 months with (history of) fever. FirstSign Malaria Pf Microscopy of thin and thick BS. 54.8% 97.9% 53.4%
Tiono[14] Children 6–59 months with (history of) fever. (High transmission) FirstSign Malaria Pf Microscopy of thin and thick BS. 76.1% 98% 25.4%
Tiono[14] Children 6–59 months with (history of) fever. (Low transmission) FirstSign Malaria Pf Microscopy of thin and thick BS. 31.8% 97.6% 63.7%
  1. *P. falciparum, **Two types of RDTs separately tested.