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Figure 3 | Malaria Journal

Figure 3

From: Four years’ monitoring of in vitro sensitivity and candidate molecular markers of resistance of Plasmodium falciparum to artesunate-mefloquine combination in the Thai-Myanmar border

Figure 3

The relationship between median IC 50 values of quinine (QN), mefloquine (MQ) and chloroquine (CQ) and the mutations of pfmdr1 and pfmrp1 gene in Plasmodium falciparum isolates. Association between (A) QN IC50 and pfmdr1 N86Y (p = 0.015, Mann–Whitney U test), S1034C (p = 0.018, Kruskal-Wallis test) and pfmrp1 F1390I mutation (p = 0.039, Mann–Whitney U test); (B) MQ IC50 and pfmdr1 N86Y mutation (p = 0.005, Mann–Whitney U test); and (C) CQ IC50 and pfmrp1 H191Y mutation (p = 0.008, Mann–Whitney U test).

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