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Table 4 Distribution of pfcrt , pfmdr1 and pvmdr1 point mutations in the investigated clinical isolates in Southern and Eastern Ethiopia

From: Return of chloroquine-sensitive Plasmodium falciparum parasites and emergence of chloroquine-resistant Plasmodium vivax in Ethiopia

  P. falciparum SE no SE (%) EE no EE (%)
Pfcrt only C72 5 2.9% 2 8.0%
  C72 and K76 4 2.4% 1 4.0%
  only K76 23 13.5% 8 32.0%
pfcrt and pfmdr1 K76 and N86 2 1.2% 2 8.0%
pfmdr1 only N86 22 12.9% 7 28.0%
  N86 and Y184 6 3.5% 2 8.0%
  only Y184 7 4.1% 3 12.0%
  P. vivax     
pvmdr1 only Y976 59 37.1% 11 19.6%
  only F1076 0    0.0%
  1. pfmdr1: Plasmodium falciparum multi-drug resistance 1; pfcrt: Plasmodium falciparum chloroquine resistance transporter; pvmdr1: Plasmodium. vivax multi-drug resistance 1; SE: Southern Ethiopia; EE: Eastern Ethiopia.