Assay | No. positive | No. negative | Sensitivity (95% CId) | Specificity (95% CI) | PPVa(95% CI) | NPVb(95% CI) | % agreement with nested PCR (Kappa) | AUCc(95% CI) |
---|---|---|---|---|---|---|---|---|
Microscopy | 96 | 81 | 75.0 (66.8-81.7) | 100 (91.1-100) | 100 (95.3-100) | 60.5 (49.6-70.4) | 81.9 (0.624) | 0.875 (0.817–0.920) |
RDT | 137 | 40 | 93.0 (87.9–96.4) | 63.3 (49.2–75.3) | 86.9 (80.1–91.6) | 77.5 (62.2–87.8) | 84.7 (0.596) | 0.781 (0.713–0.840) |
Nested PCR | 128 | 49 | Â | Â | Â | Â | Â | Â |
α-tubulin LAMP | 137 | 40 | 100 (96.4-100) | 81.6 (68.3-90.2) | 93.4 (87.8-96.6) | 100 (89.3-100) | 94.9 (0.865) | 0.908 (0.856–0.946) |