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Table 1 Kinetics determination of mAbs D2 and F9

From: Production and characterization of specific monoclonal antibodies binding the Plasmodium falciparum diagnostic biomarker, histidine-rich protein 2

mAb

ka(1/Ms)

kd(1/s)

KD(M)

D2

8.50 × 105

2.59 × 10−4

3.05 × 10−10

F9

1.80 × 106

7.66 × 10−5

4.27 × 10−11

C1-13

3.60 × 105

3.72 × 10−5

1.03 × 10−10

  1. Association (ka), dissociation rates (kd), and equilibrium constants (KD) of mAbs D2, F9, and C1-13 against rPfHRP2. The analysis for mAbs D2 and F9 were undertaken using the Octet Red platform, whereas mAb C1-13 was determined by BIAcore.
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Malaria Journal

ISSN: 1475-2875

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