Table 5 Molecular markers of anti-folate resistance in Plasmodium falciparum isolates collected through the National Antimalarial Drug Resistance Monitoring System, northeast India, 2012-2013

Quadruple

5

I 51/R 59/N 108/L 164

1

A 436/G 437/E 540/A581/T 613

35

A 436/G 437/E 540/G 581/A613

Triple

69

I 51/R 59/N 108/I164

75

A 436/G 437/E 540/A581/A613

7

N51/R 59/N 108/L 164

6

A 436/G 437/K540/G 581/A613

5

S436/G 437/E 540/G 581/A613

Double

71

N51/R 59/N 108/I164

11

S436/G 437/E 540/A581/A613

1

A 436/A437/E 540/A581/A613

2

S436/A437/E 540/G 581/A613

9

S436/G 437/K540/G 581/A613

Single

3

N51/C59/N 108/I164

1

S436/A437/E 540/A581/A613

2

S436/G 437/K540/A581/A613

1

S436/A437/K540/G 581/A613

Wild

6

S436/A437/K540/A581/A613