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Table 2 Overall performance of HRP-2 test in asymptomatic carriers across three screening campaigns

From: Lessons learned from the use of HRP-2 based rapid diagnostic test in community-wide screening and treatment of asymptomatic carriers of Plasmodium falciparum in Burkina Faso

  Campaign 1 Campaign 2 Campaign 3
Sensitivity, % (95% CI) 92.4 (91.4, 93.5) 84.0 (79.3, 88.6) 77.8 (71.5, 84.0)
Specificity, % (95% CI) 74.6 (73.1, 76.1) 87.9 (87.0, 88.7) 95.9 (95.4, 96.4)
Positive predictive value, % (95% CI) 73.8 (72.2, 75.3) 23.2 (20.3, 26.0) 35.4 (30.5, 40.2)
Negative predictive value, % (95% CI) 92.7 (91.7, 93.7) 99.2 (99.0, 99.5) 99.3 (99.1, 99.5)
False-positive rate 0.25 0.12 0.04
False-negative rate 0.08 0.16 0.22
Positive likelihood ratio 3.64 6.92 19.01
Negative likelihood ratio 0.10 0.18 0.23
Accuracy 0.82 0.88 0.95
Kappa, % (95% CI) 65.2 (63.2, 67.1) 31.9 (28.3, 35.4) 46.6 (41.4, 51.8)