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Table 1 Summary of immunization experiments

From: Immunization against a merozoite sheddase promotes multiple invasion of red blood cells and attenuates Plasmodium infection in mice

Experiment

Adjuvant

Antigen

# Mice

Infected

Pre-patency

Clearance*

Mean survival§

1

IFA

KLH

6

5/6

6.2

0/5

27.3

  

SUB2

6

6/6

6.7

4/6

34.6

2

CFA

KLH

3

3/3

6

0/3

31.3

  

SUB2

3

3/3

6.7

0/3

40+

Total

 

KLH

9

8/9

6.1

0/9

28.6

  

SUB2

9

9/9

6.7

4/9

36.4

  1. *Mice with detected parasitemia that had cleared the parasite infection (measured at Day 10).
  2. §Average number of days mice survived following P. berghei challenge.
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Malaria Journal

ISSN: 1475-2875

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