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Table 1 Interaction of oocyst an sporozoite parameters (infection rate, oocyst number and absorbance) between assay, genotype (RR, RS and SS) and genotype-strain

From: Effects of the kdr resistance mutation on the susceptibility of wild Anopheles gambiae populations to Plasmodium falciparum: a hindrance for vector control

Analysis Variable Df Statistic p
Oocyst infection rate Assay 4 LRT = 0.51 0.97
Genotype-strain 2 χ2 = 0.26 0.88
Genotype 2 χ2 = 177.9 < 2.2e-16
Strain 1 χ2 = 2.7 0.1
Sporozoite infection rate Assay 4 χ2 = 0.94 0.92
Genotype-strain 2 χ2 = 1.9 0.39
Genotype 2 χ2 = 151.7 < 2.2e-16
Strain 1 χ2 = 1.4 0.23
Oocyst number Assay (random) fem 6 AIC = 2,782 -
mm 8 AIC = 2,668
Genotype-strain 2 χ2 = 21.26 2.415e-05
Genotype No test needed since the interaction is significant
Strain
Absorbance (Sporozoite density) Assay (random) fem 8 AIC = -141 -
mm 7 AIC = -157
Genotype-strain 2 χ2 = 0.82 0.66
Genotype 2 χ2 = 81.5 3.291e-16
Strain 1 χ2 = 11.3 0.0008
  1. Random variables’ significance was evaluated by comparing the Akaike information criterion (AIC) of the most complex model, which included the random effect (mm, mixed model), and that of the same model with the random effect removed (fem, fixed-effect model). The model with the lowest AIC was chosen, i.e., the random effect was kept if the model in which it was included had the lowest AIC. The significance of fixed-effect variables was tested in a Chi-square test in the linear model of absorbance or a likelihood ratio test (which assumes a Chi-square distribution) in glm (generalized linear model), i.e., the three other analyses. The fixed-effect variable was considered significant and kept in the model if p <0.05 (in bold).