The haplotype network shows the hybrid nature of the P. vivax from southern Mexico. Two networks were constructed with 155 sequences worldwide, including the 14 Mexican sequences, according to the hypothesis that specific gene fragments based on the icb5-6 sequence correspond to two different parental lineages. The highly recombinant sites were removed to expose the genealogical relationships of the Mexican isolates. A) Complete icb5-6 fragment except sV1, B) only subfragment sV1. †Belem strain; *Sal I strain. The sizes of the nodes indicate the frequency of a particular haplotype, and colors represent different countries.