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Figure 1 | Malaria Journal

Figure 1

From: The diminishing returns of atovaquone-proguanil for elimination of Plasmodium falciparum malaria: modelling mass drug administration and treatment

Figure 1

Structure of the mathematical model. A shows the basic model unit with parasite life cycle stages in the human host, anti-malarial drug action and immunity. ‘Blood stage’ refers to individuals with asexual stage parasites in the peripheral blood but no gametocytes and ‘infectious stage’ is individuals with gametocytes. B shows the unit in A repeated three times to track parasites resistant to artemisinins and atovaquone with appearance of novel atovaquone-resistant infections indicated by alpha. C shows multiple repetitions of B to simulate treatment and/or MDA with atovaquone-proguanil, ACT and/or primaquine.

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Malaria Journal

ISSN: 1475-2875

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