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Figure 3 | Malaria Journal

Figure 3

From: Characterization of the Anopheles gambiae octopamine receptor and discovery of potential agonists and antagonists using a combined computational-experimental approach

Figure 3

Pharmacological characterization of Anopheles gambaie octopamine receptors AgOAR45A and AgOAR45B in HEK293-CRE-Luc cells. A. Dose response curves of AgOAR45A and AgOAR45B to known octopamine receptor agonists [octopamine (OA; closed circles), clonidine (closed boxes), naphazoline (closed triangles), tyramine (closed diamonds), phentolamine (open circles)]. B. Dose response curves of known octopamine receptor antagonists [chlorpromazine (closed circles), cyproheptadine (closed boxes), metaclopramide (closed triangles), promethazine (closed diamonds) of AgOAR45A and in the presence of 1 μM octopamine. Data are expressed as % 1 μM octopamine response. Means ± SD of three independent experiments are presented.

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Malaria Journal

ISSN: 1475-2875

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