Characterization of the Anopheles gambiae octopamine receptor and discovery of potential agonists and antagonists using a combined computational-experimental approach

Table 2 Binding and larvicide activity of ZINC compounds

ZINC COMPOUND	Ki (μM)	EC₅₀(μM)	IC₅₀(μM)	Larval bioassay (% mortality)
OA	7.7	0.017	-	nd*
10883478	34.2	-	55.3	74
02643656	14.9	5.6	-	nd
40118665	56.7	-	17.6	nd
48353678	2.7	22.0	-	nd
48345912	6	-	4.0	nd

ISSN: 1475-2875