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Table 3 The effect of anti-PfHRP2 antibodies on the detection of soluble PfHRP2 by RDTs

From: Circulating antibodies against Plasmodium falciparum histidine-rich proteins 2 interfere with antigen detection by rapid diagnostic tests

Culture supernatant

First response

SD

ICT

No Ab

Normal plasma

S14

S14 1:5

No Ab

Normal plasma

S14

S14 1:5

No Ab

Normal plasma

S14

S14 1:5

Undiluted

4

4

0

1

4

4

0

2

4

4

4

4

1:2

4

4

0

0

4

4

0

0

4

3

3

2

1:4

4

2

0

0

3

3

0

0

3

2

1

1

1:8

1

1

0

0

1

2

0

0

2

1

1

1

1:16

1

1

0

0

1

1

0

0

1

1

1

1

1:32

0

0

0

0

0

0

0

0

1

0

0

0

1:64

0

0

0

0

0

0

0

0

1

0

0

0

1:128

0

0

0

0

0

0

0

0

1

0

0

0