Diversity and population structure of Plasmodium falciparum in Thailand based on the spatial and temporal haplotype patterns of the C-terminal 19-kDa domain of merozoite surface protein-1

Table 1 Pairwise F _st values of Pf MSP-1 ₁₉ haplotypes between geographically isolated Plasmodium falciparum populations in Thailand

	Mae Hong Son	Ubon Ratchathani	Kanchanaburi	Trat	Ranong
Ubon Ratchathani	-0.09985	-
	(p = 0.99)
Kanchanaburi	-0.04761	-0.02984	-
	(p = 0.77)	(p = 0.56)
Trat	-0.01113	0.01017	-0.05754	-
	(p = 0.41)	(p = 0.23)	(p = 0.73)
Ranong	0.00241	-0.00344	-0.04347	-0.04642	-
	(p = 0.42)	(p = 0.39)	(p = 0.72)	(p = 0.74)
Tak*	-0.02637	-0.01682	-0.03795	-0.03720	-0.02997
	(p = 0.51)	(p = 0.55)	(p = 0.89)	(p = 0.67)	(p = 0.71)
Tak**	-0.02075	-0.00632	-0.02612	-0.01521	-0.0010
	(p = 0.4	(p = 0.46)	(p = 0.89)	(p = 0.66)	(p = 0.71)

Frequency of the Pf MSP-1₁₉ haplotypes in Tak were derived from two studies by (*) Sakihama et al., [38] and (**) Sakihama et al., [39]. All F_st values were non-significant (p > 0.05).

ISSN: 1475-2875