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Table 3 Linear regression analysis of variables contributing to urine NGAL/Ucr variability in patients with severe malaria

From: Correlation of biomarkers for parasite burden and immune activation with acute kidney injury in severe falciparum malaria

 

Univariate analysis

Multivariate model (R2 = 0.18)

Variable

β (95% CI)a

P

β (95% CI)a

P

suPAR

21.57 (12.20-30.95)

<0.001

16.54 (6.36-26.71)

0.002

Pf HRP2

0.11 (0.06-0.15)

<0.001

0.07 (0.02-0.11)

0.003

suPAR x Pf HRP2

0.002 (0.001-0.003)

<0.001

---

---

SBP

0.16 (-8.62-8.94)

0.971

---

---

Age

-12.02 (-25.32-1.28)

0.076

---

---

  1. aRegression coefficient (β) with 95% confidence intervals (CIs) showing the estimated increase in the urine concentration of NGAL (pg/ml) corrected for urine creatinine (uNGAL/Ucr pg/mg of creatinine) predicted by 1 unit increases in the independent (predictor) variables using robust regression analysis. Significant in bold.