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Table 3 Linear regression analysis of variables contributing to urine NGAL/Ucr variability in patients with severe malaria

From: Correlation of biomarkers for parasite burden and immune activation with acute kidney injury in severe falciparum malaria

  Univariate analysis Multivariate model (R2 = 0.18)
Variable β (95% CI)a P β (95% CI)a P
suPAR 21.57 (12.20-30.95) <0.001 16.54 (6.36-26.71) 0.002
Pf HRP2 0.11 (0.06-0.15) <0.001 0.07 (0.02-0.11) 0.003
suPAR x Pf HRP2 0.002 (0.001-0.003) <0.001 --- ---
SBP 0.16 (-8.62-8.94) 0.971 --- ---
Age -12.02 (-25.32-1.28) 0.076 --- ---
  1. aRegression coefficient (β) with 95% confidence intervals (CIs) showing the estimated increase in the urine concentration of NGAL (pg/ml) corrected for urine creatinine (uNGAL/Ucr pg/mg of creatinine) predicted by 1 unit increases in the independent (predictor) variables using robust regression analysis. Significant in bold.