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Relevance of K13 mutations for malaria control and elimination program

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The K13 gene mutations have been found to be associated with artemisin resistance in Cambodia, although the relevance of these mutations on artemisinin resistance in other endemic areas have to be better documented. We present here new data on K13 mutations and on the artemisinin resistance outside Cambodia. We propose to open the discussion about how these new findings have to be interpreted regarding the emergence and spread of artemisinin resistance and their usefulness to identify and prevent the spread of resistant strains in order to reach the malaria control and elimination global program goal.

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Correspondence to Frédéric Ariey.

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This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.

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Ariey, F. Relevance of K13 mutations for malaria control and elimination program. Malar J 13, O40 (2014) doi:10.1186/1475-2875-13-S1-O40

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  • Infectious Disease
  • Malaria
  • Gene Mutation
  • Endemic Area
  • Resistant Strain


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