Table 1 Abbreviations, Eisenberg hydropathy (EIS) value, side-chain volume (SCV), side-chain pKa and formal charge on the side-chain for amino acids.
Amino-acid | EIS hydropathy (log scale) | side-chain volume Ã…3 | side-chain pKa | formal side-chain charge (pH 7.0) |
|---|---|---|---|---|
A ala | 0.25 | 156.55 | Â | 0 |
C cys | 0.04 | 219.43 | 8.33 | 0 |
D asp | -0.72 | 232.12 | 3.86 | -1 |
E glu | -0.62 | 284.70 | 4.25 | -1 |
F phe | 0.61 | 382.16 | Â | 0 |
G gly | 0.16 | 85.18 | Â | 0 |
H his | -0.40 | 334.84 | 6.0 | +1 |
I ile | 0.73 | 313.43 | Â | 0 |
K lys | -1.10 | 366.25 | 10.28 | +1 |
L leu | 0.53 | 315.53 | Â | 0 |
M met | 0.26 | 327.41 | Â | 0 |
N asn | -0.64 | 256.12 | Â | 0 |
P pro | -0.07 | ND | Â | 0 |
Q gln | -0.69 | 308.35 | Â | 0 |
R arg | -1.80 | 421.32 | 12.48 | +1 |
S ser | -0.26 | 183.07 | Â | 0 |
T thr | -0.18 | 238.55 | Â | 0 |
V val | 0.54 | 267.78 | Â | 0 |
W trp | 0.37 | 462.28 | Â | 0 |
Y tyr | 0.02 | 407.07 | 10.07 | 0 |