Figure 2

Distribution of the OD₄₉₂ data for sera from individuals with patent P. vivax malaria, from individuals exposed to P. falciparum, from individuals with unrelated diseases or healthy controls. The symbols represent the reactivity of each serum sample tested in duplicate at 1:100 dilution against the indicated recombinant proteins. The abbreviations are as follow: A) Pv= individuals with P. vivax malaria (n = 200), B) Pf= individuals from areas where P. falciparum malaria is endemic (n = 53), C) Cha = individuals with Chagas Disease (n = 21), D) Syp = individuals with syphilis (n = 21), E) HBV = individuals with hepatitis B (n = 19), F) HCV= individuals with hepatitis C (n = 21), G) HTLV = individuals with HTLV (n = 14), H) HIV= individuals with HIV (n = 12), I) ANA = individuals positive for antinuclear antibodies (n = 10), J) RF = individuals positive for rheumatoid factors (n = 10), L) Healthy = Healthy individuals (n = 49). Sera from African individuals exposed to P. falciparum were tested only against recombinant protein His₆-MSP1_19. The horizontal line inside the drops for each recombinant protein represents the cut-off values (0.127, 0.170, 0.198 and 0.500 for GST-MSP1₁₉, His₆-MSP1₁₉, His₆-MSP1₁₉-PADRE and yMSP1₁₉-PADRE, respectively).