Table 2 Enzymes of the pentose phosphate pathway and pyridine nucleotide metabolism. Enzymes are grouped into pathways. They are given by their name, their EC numbers, the gene identification (PfID) in the Plasmodium genome database (PlasmoDB)), the time (in hours post invasion (HPI)) in the parasite's developmental cycle when they are maximally transcribed obtained from the IDC database and the metabolic function of the enzyme.

Pentose phosphate pathway

Glucose-6-phosphate dehydrogenase

1.1.1.49

PF14_0511

48

6-phosphogluconolactonase

3.1.1.31

PF14 0511

48

6-phosphogluconate dehydrogenase

1.1.1.44

PF14_0520

26

Ribulose 5-phosphate 3-epimerase

5.1.3.1

PFL0960w

29

Ribose 5-phosphate isomerase

5.3.1.6

PFE0730c

21

Transketolase

2.2.1.1

MAL6P1.110

17

Ribose phosphate diphosphokinase

2.7.6.1

PF13 0143 PF13 0157

21 21

Deoxyribose phosphate aldolase

4.1.2.4

PF10 0210

21

Phosphoglucomutase

5.4.2.2

PF10 0122

21

Nicotinamidase

3.5.1.19

chr3.glm 243

18, 38

Nicotinatephosphoribosyl transferase

2.4.2.11

chr6.glm_337

25

Nicotinate-nucleotide adenylyl transferase

2.7.7.18

chr13.glm_329

20, 40

NAD⁺ synthetase

6.3.5.1

PFI1310w

28

Pyridine nucleotide transhydrogenase

1.6.1.1.

PF14_0508

32

Hydroxyethylthiazole kinase

2.7.1.50

PFL1920c

22

Hydroxymethylpyrimidine kinase/ Phosphomethylpyrimidine kinase

2.7.149 2.7.4.7

PFE1030c

33

Thiamine-phosphate diphosphorylase

2.5.1.3

MAL6P1.285

1

Thiamine diphosphokinase

2.7.6.2

PFI1195c

28