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Table 1 Comparison of P. falciparum and P. vivax passive and active case detection. The study includes individuals followed throughout the year-2003 malaria transmission season (February-July, 2003). Passive case detection was conducted at the Health Post, where individuals presenting with febrile illness are tested for malaria parasites by microscopy. Active case detection was performed in two ways. In March, a community survey was conducted where 957 of the population (N = 1907) were sampled. Then, April-July, sentinel individuals living in houses defined as at-risk zones for P. falciparum transmission were randomly selected. Individuals selected as sentinels were followed prospectively for one month with weekly visits. The passive and "passive and active" (active+passive) prevalence only considers individuals who were enrolled both in the community survey and enrolled as sentinels in at-risk zones for at least one month during these months.

From: Clustered local transmission and asymptomatic Plasmodium falciparum and Plasmodium vivax malaria infections in a recently emerged, hypoendemic Peruvian Amazon community

 

P. falciparum

P. vivax

Total malaria cases detected by passive case detection February - July, 2003 / total population

49/1907 = 0.03

418/1907 = 0.22

No. monthly active case intervals with weekly sampling in at-risk zones (No. of individuals)

592 (573)

592 (573)

Malaria infections detected by active+passive surveillance in at-risk zone sentinels

Total: 74/573 = 0.13

Total: 224/573 = 0.39

Passive case detection, February – July

15a (20.8%)

48 (21.4%)

Community survey, March

12b (16.7%)

36b (16.1%)

Monthly active surveillance in at-risk zones, April – July

46 (62.5%)

140 (62.5%)

Difference in passive versus active+passive prevalence Attributable fraction potentially explained by sampling in at-risk zones and/or asymptomatic infections

0.13/0.03 = 4.33

0.39/0.22 = 1.77

  1. a Of the remaining 34 P. falciparum infections detected in passive case detection, but not included in this count, at least 12 occurred in individuals living within at-zones. This is because these individuals were not selected as sentinels for the weekly active surveillance.
  2. b Five additional P. falciparum and 36 additional P. vivax infections were detected in the community survey. However, they occurred in individuals not selected as sentinels for the weekly active surveillance.