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Table 4 Genotypes of IL1B -31C>T and TNFA -308G>A in Thai malaria patients.

From: A functional polymorphism in the IL1B gene promoter, IL1B -31C>T, is not associated with cerebral malaria in Thailand

 

TNFA -308G>A

 

G/G

G/A

A/A

Mild malaria (n = 192)

   

IL1B -31C>T

   

C/Cb

48 (0.250)

7 (0.036)

0 (0.000)

C/T

85 (0.443)

6 (0.031)

0 (0.000)

T/T

43 (0.224)

3 (0.016)

0 (0.000)

Cerebralmalaria (n = 105)

   

IL1B -31C>T

   

C/C

25 (0.238)

2 (0.019)

0 (0.000)

C/T

41 (0.390)

8 (0.076)

0 (0.000)

T/T

25 (0.238)

3 (0.029)

1 (0.009)

  1. Frequencies are in parentheses.
  2. There was no significant difference in each genotype frequency between mild and cerebral malaria by the Fisher's exact test based on 2 × 2 contingency table where all the other genotypes are combined.
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Malaria Journal

ISSN: 1475-2875

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