Table 1 Associations between dhfr and crt mutations in 126 Ghanaian children with uncomplicated malaria
From: Concurrence of Plasmodium falciparum dhfr and crt mutations in northern Ghana
dhfr mutation | Prevalence of crt T76 mutation (%) | Odds ratio (95%CI) of crt T76 being present | |||
|---|---|---|---|---|---|
Unadjusted | P | Adjusted for CQ in blood* | P | ||
51 | |||||
absent | 67.9 (38/56) | 1 | 1 | ||
present | 90.0 (63/70) | 4.3 (1.5–12.5) | 0.002 | 5.0 (1.8–13.8) | 0.002 |
59 | |||||
absent | 63.6 (28/44) | 1 | 1 | ||
present | 89.0 (73/82) | 4.6 (1.7–13.0) | 0.0007 | 4.4 (1.7–11.4) | 0.002 |
108 | |||||
absent | 65.7 (23/35) | 1 | 1 | ||
present | 85.7 (78/91) | 3.1 (1.2–8.6) | 0.01 | 3.2 (1.2–8.2) | 0.02 |
triple | |||||
absent | 68.7 (46/67) | 1 | 1 | ||
present | 93.2 (55/59) | 6.3 (1.9–26.6) | 0.0006 | 7.0 (2.2–22.5) | 0.001 |