Skip to main content

Table 2 cDNA microarray analysis of immunomodulator gene expression in P. yoelii 17XL infected mouse brain at peak parasitemia (day eight post-infection).

From: Plasmodium yoelii 17XL infection up-regulates RANTES, CCR1, CCR3 and CCR5 expression, and induces ultrastructural changes in the cerebellum

GENE NAME FOLD CHANGE EXPRESSION DESCRIPTION OF GENE
PECAM-1 23.0 Platelet Endothelia Cell Adhesion Molecule-1
ICAM-1 13.0 Intercellular Adhesion Molecule-1
VCAM-1 6.0 Vascular Cell Adhesion Molecule-1
RANTES 6.0 Regulated upon Activation Normal T cell Expressed and Secreted
INF-γ 6.0 Interferon-gamma
TNF 5.0 Tumor Necrosis Factor-alpha
IL-12 4.0 Interleukin-12
CCR1 4.0 C-C chemokine receptor 1
CCR3 4.0 C-C chemokine receptor 3
CCR5 4.0 C-C chemokine receptor 5
iNOS 4.0 Inducible Nitric Oxide Synthase
ZO-1 2.0 Zonula Occludin -1
IL-4 2.0 Interleukin-4
GDF-2 -2.0 Growth differentiation factor-2
TGF-α -2.0 Tumor growth factor-alpha
GAPDH 0.0 Glyceraldehyde-3-Phosphate Dehydrogenase
  1. P. yoelii 17XL infection alters immunomudulator gene expression in mouse brain at peak parasitemia (day eight post-infection). cDNA microarray analysis of P. yoelii 17XL infected and uninfected mouse brain. Gene listed were altered > 1.5 fold at peak parasitemia. Fold change in expression is defined as GAPDH normalized mRNA expression ratio of gene signals of infected to uninfected mouse brain.
\