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Table 2 Antimalarial drugs administered in eight studies of treatment response. Antioquia (Colombia), 2000–2004 (1)

From: Therapeutic efficacy test in malaria falciparum in Antioquia, Colombia

Treatment Total Dose Rescue Treatment
Chloroquine 25 mg/kg: 10 mg/kg day 1; 7.5 mg/kg days 1 and 2 Quinine sulphate – CL
Amodiaquine 25 mg/kg: 10 mg/kg day 1; 7.5 mg/kg days 1 and 2 Mefloquine – SP
Mefloquine 15 mg/kg only one dose on the day 1 Quinine sulphate – SP
Sulphadoxine-pyrimethamine (SP) 25 mg/kg S + 1.25 mg/kg P only one dose day 1 Quinine sulphate – CL
Chloroquine-SP 25 mg/kg: 10 mg/kg day 1; 7.5 mg/kg days 1 and 2 Quinine sulphate – CL
  25 mg/kg S + 1.25 mg/kg P only one dose day 1  
Amodiaquine-SP 25 mg/kg: 10 mg/kg day 1; 7.5 mg/kg days 1 and 2 Mefloquine
  25 mg/kg S + 1.25 mg/kg P only one dose day 1  
Mefloquine-SP 15 mg/kg only one dose day 1 Amodiaquine – SP
  25 mg/kg S + 1.25 mg/kg P only one dose day 1  
Artesunate-SP 12 mg/kg: 4 mg/kg días 0, 1 y 2 Amodiaquine – SP
  25 mg/kg S + 1.25 mg/kg P only one dose day 1  
  1. (1) S sulphadoxine, P pyrimethamine, SP sulphadoxine-pyrimethamine, CL clindamicine.
  2. AQ year 2002 lot 00L22/0439E tab 150 mg Alkem Laboratory; year 2003 lot 3001-ET, Alkem Laboratory.
  3. MQ year 2002 lot 51009 tab 250 mg, Mepha Laboratory; year 2003: lot 350866, Mepha Laboratory.
  4. SP years 2000–2001 lot Sul 50600606; year 2002 lot 09017 RE tab500/25 mg, VAP Laboratory; year 2003–2004: lot RJ0002, Roche Laboratory.
  5. AS lot 351237 Mepha Laboratory.
  6. CQ lot C141100.
  7. QN lot 98C12.
  8. CL lot 000101