Therapeutic efficacy test in malaria falciparum in Antioquia, Colombia

Malaria Journal

Table 2 Antimalarial drugs administered in eight studies of treatment response. Antioquia (Colombia), 2000–2004 (1)

Treatment	Total Dose	Rescue Treatment
Chloroquine	25 mg/kg: 10 mg/kg day 1; 7.5 mg/kg days 1 and 2	Quinine sulphate – CL
Amodiaquine	25 mg/kg: 10 mg/kg day 1; 7.5 mg/kg days 1 and 2	Mefloquine – SP
Mefloquine	15 mg/kg only one dose on the day 1	Quinine sulphate – SP
Sulphadoxine-pyrimethamine (SP)	25 mg/kg S + 1.25 mg/kg P only one dose day 1	Quinine sulphate – CL
Chloroquine-SP	25 mg/kg: 10 mg/kg day 1; 7.5 mg/kg days 1 and 2	Quinine sulphate – CL
	25 mg/kg S + 1.25 mg/kg P only one dose day 1
Amodiaquine-SP	25 mg/kg: 10 mg/kg day 1; 7.5 mg/kg days 1 and 2	Mefloquine
	25 mg/kg S + 1.25 mg/kg P only one dose day 1
Mefloquine-SP	15 mg/kg only one dose day 1	Amodiaquine – SP
	25 mg/kg S + 1.25 mg/kg P only one dose day 1
Artesunate-SP	12 mg/kg: 4 mg/kg días 0, 1 y 2	Amodiaquine – SP
	25 mg/kg S + 1.25 mg/kg P only one dose day 1

(1) S sulphadoxine, P pyrimethamine, SP sulphadoxine-pyrimethamine, CL clindamicine.
AQ year 2002 lot 00L22/0439E tab 150 mg Alkem Laboratory; year 2003 lot 3001-ET, Alkem Laboratory.
MQ year 2002 lot 51009 tab 250 mg, Mepha Laboratory; year 2003: lot 350866, Mepha Laboratory.
SP years 2000–2001 lot Sul 50600606; year 2002 lot 09017 RE tab500/25 mg, VAP Laboratory; year 2003–2004: lot RJ0002, Roche Laboratory.
AS lot 351237 Mepha Laboratory.
CQ lot C141100.
QN lot 98C12.
CL lot 000101

ISSN: 1475-2875