Table 2 Final main effects linear model of the association between baseline explanatory variables and day 3 lumefantrine concentration in ng/mL (456 patients).

female gender

791.4

125.2

1493.3

0.019

unsupervised treatment

-2538.2

-2995.0

-2046.8

<0.0001

age

   ≥15 years

[reference]

0.358

   5–14 years

322.5

-657.8

1388.6

0.530

   <5 years

462.3

-478.7

1480.2

0.345

lumefantrine dose (mg/Kg)

   ≥80

[reference]

0.033

   65–79

-463.2

-1336.2

488.2

0.329

   50–64

-1009.2

-1892.5

-35.4

0.043

   <50

-1237.2

-2386.6

79.5

0.064

history of vomiting at inclusion

-688.6

-1294.1

-44.8

0.036

constant

5778.1

4313.1

7457.0