Day 3 | Day 7 | Day 14 | Day 28 | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
SP | AL | P | SP | AL | P | SP | AL | P | SP | AL | P | |
N | 430 | 451 | 405 | 436 | 384 | 406 | 290 | 320 | ||||
Fever (%) | 3.5 | 0.9 | 0.007 | 1.0 | 1.1 | 0.55 | 1.3 | 1.0 | 0.75 | 2.7 | 1.2 | 0.19 |
Parasitaemia | 15.0 | 0.7 | <0.001 | 2.0 | 0.0 | NA | 2, | 0;5 | 0.009 | 5.5 | 1.2 | 0.003 |
Hemoglobin (mean)*(g/L) | - | - | - | - | 124 | 129 | 0.003 | 130 | 134 | 0.02 | ||
Gametocyte carriage (N (%)) | 33 (7.6) | 3 (0.7) | <0.001 | 88 (21.6) | 2 (0.5) | <0.001 | 76 (19.8) | 0 (0) | NA | 10 (4.5) | 1 (0,3) | 0.004 |
Gametocyte densities (range) | 48.6 (1–4320) | 6.2 (1–240) | 0.62 | 63.6 (1–4480) | 8.9 (1–80) | 0.51 | 52.8 (1–6960) | 0(0) | NA | 154.9 (3–840) | 160 | NA |
N | 430 | 448 | 400 | 428 | 382 | 401 | 303 | 329 | ||||
Weakness (%) | 46.3 | 20.5 | <0.001 | 15.0 | 6.1 | <0.001 | 7.1 | 3.7 | 0.04 | 5.9 | 3.0 | 0.08 |
Headache (%) | 45.6 | 22.5 | <0.001 | 18.0 | 12.2 | 0.02 | 10.7 | 8.5 | 0.28 | 11.5 | 10.3 | 0.62 |
Muscle joint pain (%) | 20.3 | 8.2 | <0.001 | 5.2 | 2.6 | 0.004 | 3.8 | 2.8 | 0.47 | 2.3 | 2.8 | 0.73 |
Dizziness (%) | 20.0 | 10.8 | <0.001 | 5.2 | 3.0 | 0.11 | 2.1 | 1.0 | 0.21 | 2.7 | 1.2 | 0.18 |
Nausea (%) | 15.8 | 2.9 | <0.001 | 1.3 | 0.0 | NA | 0.8 | 0.5 | NA | 0.7 | 0.6 | NA |
Vomiting (%) | 5.8 | 0.7 | <0.001 | 0.5 | 0.2 | NA | 0.5 | 0.5 | NA | 0.0 | 0.3 | NA |
Diarrhoea (%) | 3.8 | 7.7 | 0.013 | 0,9 | 2.5 | 0.08 | 1.3 | 2.7 | 0.16 | 0.7 | 1.2 | 0.78 |
Abdominal pain (%) | 16.7 | 9.2 | <0.001 | 7.0 | 4.0 | 0.06 | 3.4 | 3.5 | 0.94 | 5.0 | 3.7 | 0.41 |
Hear palpitations (%) | 9.8 | 5.1 | 0.008 | 5.5 | 4.2 | 0.38 | 5.8 | 8.0 | 0.61 | 4.6 | 7.3 | 0.88 |
Back ache (%) | 10.9 | 8.9 | 0.32 | 7.0 | 7.7 | 0.53 | 5.8 | 8.0 | 0.22 | 4.6 | 7.3 | 0.15 |