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Table 2 Proportions of point mutations on dhfr and dhps related to parasite resistance to antifolates

From: Drug resistance to sulphadoxine-pyrimethamine in Plasmodium falciparum malaria in Mlimba, Tanzania

Resistance to Gene locus Mutations (%) Wild type (%) Mixed (%) Total
Pyrimethamine DHFR 51 74 (62.7%) 35 (29.7%) 9 (7.6%) 118
  DHFR 59 59 (48.8%) 36 (29.8%) 26 (21.5%) 121
  DHFR 108 81 (66.9%) 17 (14.1%) 23 (19.0%) 121
  DHFR 164 0 (0.0%) 104 (100.0%) 0 (0.0%) 104
Sulphadoxine DHPS 437 56 (43.7%) 71 (55.5%) 1 (0.8%) 128
  DHPS 540 47 (39.2%) 65 (54.5%) 8 (6.3%) 120
  DHPS 581 1 (0.8%) 126 (98.4%) 1 (0.8%) 128
   318 454 68 840