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Table 2 The gametocyte rate – gametogenesis – and gametocyte longevity (gametocytogenesis) in malaria infections caused by wild-type parasites and parasites with different number of dhfr/dhps mutations (MOM 1 – 5). The differences in gametogenesis between parasites with different MOM were estimated by calculation of the Odd ratios with reference to MOM5.

From: The implication of dihydrofolate reductase and dihydropteroate synthetase gene mutations in modification of Plasmodium falciparum characteristics

Gametocytogenesis
  Gametogenesis Gametocyte longevity
  Yes No Odd Ratio 95% CI        
     Lower Upper 0 1 2 3 4 5 6 (max)
*Wild (4) 0 1.0 3.330 1.707 6.511 1.0 0 0 0 0 0 0
*Single (5) 0 1.0 3.330 1.707 6.511 1.0 0 0 0 0 0 0
Double (10) 0.60 0.40 1.556 0.319 7.597. 0.40 0.20 0.30 0.10 0 0 0
Triple (21) 0.62 0.38 1.436 0.391 5.269 0.38 0.33 0.19 0.05 0 0.05 0
Quadruple (93) 0.69 0.31 1.057 0.364 3.028 0.31 0.24 0.23 0.17 0.05 0 0
Quintuple (20) 0.70 0.30 1.000 0 0 0.30 0.20 0.30 0.15 0.05 0 0
  1. * In the two groups the test parameters were significantly lower than in the other groups
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Malaria Journal

ISSN: 1475-2875

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