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Table 2 The gametocyte rate – gametogenesis – and gametocyte longevity (gametocytogenesis) in malaria infections caused by wild-type parasites and parasites with different number of dhfr/dhps mutations (MOM 1 – 5). The differences in gametogenesis between parasites with different MOM were estimated by calculation of the Odd ratios with reference to MOM5.

From: The implication of dihydrofolate reductase and dihydropteroate synthetase gene mutations in modification of Plasmodium falciparum characteristics

Gametocytogenesis

 

Gametogenesis

Gametocyte longevity

 

Yes

No

Odd Ratio

95% CI

       
    

Lower

Upper

0

1

2

3

4

5

6 (max)

*Wild (4)

0

1.0

3.330

1.707

6.511

1.0

0

0

0

0

0

0

*Single (5)

0

1.0

3.330

1.707

6.511

1.0

0

0

0

0

0

0

Double (10)

0.60

0.40

1.556

0.319

7.597.

0.40

0.20

0.30

0.10

0

0

0

Triple (21)

0.62

0.38

1.436

0.391

5.269

0.38

0.33

0.19

0.05

0

0.05

0

Quadruple (93)

0.69

0.31

1.057

0.364

3.028

0.31

0.24

0.23

0.17

0.05

0

0

Quintuple (20)

0.70

0.30

1.000

0

0

0.30

0.20

0.30

0.15

0.05

0

0

  1. * In the two groups the test parameters were significantly lower than in the other groups