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Figure 6 | Malaria Journal

Figure 6

From: Induction of multi-antigen multi-stage immune responses against Plasmodium falciparum in rhesus monkeys, in the absence of antigen interference, with heterologous DNA prime/poxvirus boost immunization

Figure 6

Effect of CRL1005 formulation on frequencies of IFN-γ ELIspot responders in (A) Pf CSP or (B) CSLAM immunized monkeys. Monkeys were immunized with either Pf CSP or CSLAM in PBS (open circle) or formulated in CRL1005 (solid circle). PBMC were collected at time points as defined in the legend to Figure 2 and assayed against recombinant Pf CSP, Pf LSA1, Pf AMA1 or Pf MSP1 protein and Pf SSP2/TRAP peptide pools by IFN-γ ELIspot. Data represent the number of animals with responses that met the defined criteria of positivity (SFC = 25 and SI = 2).

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Malaria Journal

ISSN: 1475-2875

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