Figure 1
Prevalence of IgG antibody in patients at day 0 to different malaria antigens in relation to treatment outcome. Black: Parasitological or clinical treatment failure (TF), White: Adequate clinical and parasitological response (ACPR). Patients receiving sulphadoxine-pyrimethamine (SP) or amodiaquine (AQ) are grouped together. Error bars illustrate 95% confidence intervals. χ2 test were done to compare proportions of IgG antibody responders between treatment outcome groups. Only significant p-values are presented. aGLURP-R0; χ2 = 20.9, bGLURP-R2; χ2 = 12.7. GLURP-R0: Glutamate-rich Protein region N-terminal, GLURP-R2: Glutamate-rich Protein region C-terminal, AMA1: Apical Membrane Antigen 1, CSP: Circumsporozoite Protein, EBA: Erythrocyte Binding Antigen-175, CIDR: CIDR domain of PfEMP1 (PFD1235w), DBL2: DBL2 domain of PfEMP1 (PF13_0003), DBL4: DBL4 domain of PfEMP1 (PFD1235w), MSP1: Merozoite Surface Protein 1, MSP3: Merozoite Surface Protein 3, VSA1: Variant Surface Antigen on unselected 3D7 parasite strain, VSA2: Variant Surface Antigen on bone marrow selected 3D7 parasite strain. SCHIZONT: Crude extract of schizont material.