Sequence diversity and natural selection at domain I of the apical membrane antigen 1 among Indian Plasmodium falciparum populations

Table 2 Comparison of different estimates of recombination events between all five study areas

Regions	R^a	R^b	Rm
Assam (n = 28)	0.178	81	9
Orissa (n = 35)	0.118	53.7	11
A & N (n = 40)	0.057	26	7
UP (n = 36)	0.016	7.5	8
Goa (n = 18)	0.074	33.7	6
Total (n = 157)	0.123	56.2	12

Note: The R and Rm were estimated excluding the sites containing alignment gaps or those segregating for three nucleotides. The R was computed using R = 4Nr, where N is the population size and r is the recombination rate per sequence (per gene) n, number of isolates; R^a, recombination parameter between adjacent sites; R^b, recombination parameter for entire gene; Rm, minimum number of recombination events between adjacent sites

ISSN: 1475-2875