1997
|
2000
|
2001
|
2002
|
2003
|
2004
|
Normality
|
---|
Variable
|
N
|
Mean
|
STD
|
N
|
Mean
|
STD
|
N
|
Mean
|
STD
|
N
|
Mean
|
STD
|
N
|
Mean
|
STD
|
N
|
Mean
|
STD
|
p-value
|
---|
Means (raw values)
|
CQ
|
31
|
236
|
203.4
|
33
|
173.2
|
223
|
31
|
251.4
|
236.7
|
46
|
131.3
|
104
|
34
|
143.8
|
91.03
|
67
|
171.5
|
157.2
|
0.01
|
QN
|
46
|
234.6
|
150.2
|
28
|
305.8
|
210.4
|
31
|
444
|
286.2
|
40
|
252.6
|
273.6
|
34
|
280.8
|
162.8
|
58
|
207.5
|
149.8
|
0.01
|
MdAQ
|
45
|
12.8
|
12.4
|
33
|
85.1
|
167.8
|
31
|
57.7
|
63.2
|
43
|
42.9
|
32.3
|
34
|
31.1
|
21.3
|
64
|
21.7
|
17.6
|
0.01
|
ART
|
10
|
3.6
|
0.8
|
31
|
9.8
|
12.0
|
31
|
6.1
|
6.6
|
40
|
5.7
|
4.5
|
34
|
7.4
|
5.9
|
36
|
7.5
|
5.0
|
0.01
|
Means (natural log values)
|
CQ
|
31
|
4.9
|
1.4
|
33
|
4.4
|
1.2
|
31
|
5
|
1.2
|
46
|
4.5
|
0.9
|
34
|
4.7
|
0.8
|
67
|
4.7
|
1
|
0.01
|
QN
|
46
|
5.2
|
0.8
|
28
|
5.5
|
0.8
|
31
|
5.9
|
0.7
|
40
|
5.1
|
0.9
|
34
|
5.5
|
0.5
|
58
|
5.1
|
0.8
|
0.04
|
MdAQ
|
45
|
2.1
|
0.9
|
33
|
3.8
|
1.0
|
31
|
3.6
|
0.9
|
43
|
3.5
|
0.7
|
34
|
3.2
|
0.6
|
64
|
2.8
|
0.9
|
0.04
|
ART
|
10
|
1.2
|
0.3
|
31
|
1.8
|
1.0
|
31
|
1.3
|
1
|
40
|
1.3
|
1.0
|
34
|
1.8
|
0.6
|
36
|
1.8
|
0.7
|
0.15
|
Geometric means
|
CQ
|
31
|
130.3
|
3.9
|
33
|
82.3
|
3.5
|
31
|
148.4
|
3.2
|
46
|
93.7
|
2.5
|
34
|
112.2
|
2.2
|
67
|
115.6
|
2.7
|
-
|
QN
|
46
|
181.3
|
2.3
|
28
|
237.5
|
2.2
|
31
|
350.7
|
2.1
|
40
|
169.0
|
2.6
|
34
|
244.7
|
1.7
|
58
|
162.4
|
2.1
|
-
|
MdAQ
|
45
|
8.5
|
2.5
|
33
|
43.8
|
2.7
|
31
|
38.5
|
2.4
|
43
|
33.1
|
2.1
|
34
|
25.3
|
1.9
|
64
|
15.8
|
2.4
|
-
|
ART
|
10
|
3.5
|
1.3
|
31
|
5.8
|
2.7
|
31
|
3.9
|
2.7
|
40
|
3.9
|
2.8
|
34
|
6.1
|
1.9
|
36
|
6.0
|
2.0
|
-
|
Geometric Least Squares Means
|
CQ
|
31
|
130.8
|
1.2
|
33
|
82.6
|
1.2
|
31
|
148.4
|
1.2
|
46
|
93.3
|
1.2
|
34
|
112.7
|
1.2
|
67
|
115
|
1.1
|
-
|
QN
|
46
|
181.3
|
1.1
|
28
|
238.2
|
1.2
|
31
|
350.1
|
1.1
|
40
|
168.4
|
1.1
|
34
|
245
|
1.1
|
58
|
162.2
|
1.1
|
-
|
MdAQ
|
45
|
8.5
|
1.1
|
33
|
44
|
1.2
|
31
|
38.5
|
1.2
|
43
|
33.1
|
1.1
|
34
|
25.3
|
1.2
|
64
|
15.9
|
1.1
|
-
|
ART
|
10
|
3.5
|
1.3
|
31
|
5.8
|
1.2
|
31
|
3.9
|
1.2
|
40
|
3.9
|
1.1
|
34
|
6.1
|
1.2
|
36
|
6.0
|
1.1
|
-
|
- P-values are from the Kolmogorov-Smirnov test for normality. CQ = chloroquine; QN = quinine; MdAQ = monodesethylamodiaquine; ART = artemisinin