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Table 1 Prevalence of pfcrt alleles (codons 72–76) in malaria-endemic regions of PNG

From: Microsatellite polymorphism within pfcrt provides evidence of continuing evolution of chloroquine-resistant alleles in Papua New Guinea

 

Early 1980'sa

Post-1995

 

Community

Clinical

Allele

n = 7

Liksulb

n = 22

Dreikikirc

n = 31

Woserad

n = 166

Woserae

n = 595

CVMNK

0.143

0.045

0.484

0.241

0.097

SVMNT

0.857

0.955

0.516

0.572

0.791

CVIET

0

0

0

0.006f

0.013

CVMNK + SVMNT

0

0

0

0.181

0.086

CVMNK + CVIET

0

0

0

0

0.002

SVMNT + CVIET

0

0

0

0

0.012

  1. a, b, c Samples with mixed infections were not included.
  2. a Samples were collected from the Eastern Highlands (n = 1), East Sepik (n = 3), Manus (n = 1), Milne Bay (n = 1), and Morobe (n = 1) provinces of PNG between 1982 and 1984 and were previously reported [8].
  3. b, c Samples were collected in 1996 and were previously reported [7].
  4. d Samples were collected in 1998 and 2002. The 1998 samples were previously reported [7].
  5. e Samples were collected between 2001 and 2003 in local health centers.
  6. f Allele found only in samples taken from the 2002 group.