Table 4 Estimates of EC50 obtained from fitting the 3-parameter sigmoid curve to the data presented in the Example using WinBUGS, with upper boundary of γ set to 30 or 50.
Isolate | Posterior Estimate of EC50– median (95% range) | |
|---|---|---|
|  | γ = 30 | γ = 50 |
Artesunate (A) | 22.2 (18.6 – 28.2) | 21.9 (18.0 – 29.8) |
Halofantrine (B) | 46.5 (37.3 – 60.0) | 45.2 (36.0 – 60.0) |
Mefloquine (C) | 165 (134 – 205) | 161 (128 – 210) |
Mefloquine (D) | 157 (123 – 212) | 153 (121 – 215) |
Chloroquine (E) | 913 (731 – 1260) | 888 (719 – 1282) |
Chloroquine (F) | 539 (465 – 649) | 540 (462 – 660) |