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Table 1 Demographic and clinical characteristics of the study population according to treatment group on day 0.

From: Efficacy and tolerability of four antimalarial combinations in the treatment of uncomplicated Plasmodium falciparum malaria in Senegal

  Artesunate-amodiaquine N = 360 Artesunate-mefloquine N = 145 Artemether-lumefantrine (four-doses) N = 140 Artemether-lumefantrine (six-doses) N = 149 Amodiaquine-sulphadoxine-pyrimethamine N = 161
Mean age (yrs) 15 15 12 13 12
Range 1–75 2–65 2–63 2–60 2–51
Mean wt (kg) 36 37 32 35 37
Range 5–102 11–110 12–83   6–89
Mean Parasitaemia (parasites/μL) 39800 27000 22000 15398 27000
Hb < 12 g/dL 68.6% 62.5% 96.7% 68.6% 70.3%
SGOT > 30 UI/L 15.2% 0% 9.7% 17.1% 0%
SGPT > 35 UI/L 0% 0% 0% 2.8% 0%
Creatininemia > 14 mg/L 0% 0% 0% 30% 0%