Figure 4

Effect of anti-CD8 antibodies on the mortality and course of infection in mice infected with P. berghei ANKA or co-infected with T. cruzi G strain. Of five groups of C57BL/6 mice, three were inoculated with T. cruzi metacyclic forms. Fifteen days later, P. berghei-parasitized erythrocytes were given to two uninfected groups (each n = 5), two T. cruzi-infected group (each n = 5), whereas one group remained infected with T. cruzi only (n = 5). On day 0 and 5 of malaria infection, one P. berghei-infected and one co-infected group were treated with anti-CD8 antibodies. B) Parasitaemia of P. berghei is expressed in percentage of parasitized erythrocytes and the values indicate the means ± SD.