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Table 5 IgG subclass levels separated by FcγRIIa R131H genotypes and alleles in the Fulani and Dogon ethnic groups

From: Differences in Fcgamma receptor IIa genotypes and IgG subclass pattern of anti-malarial antibodies between sympatric ethnic groups in Mali

  Dogon Fulani
  no. age IgG1 IgG2 IgG3 IgG4 no. age IgG1 IgG2 IgG3 IgG4
H/H 24 15 15 ± 2.9 0.4 ± 5.6 4.5 ± 3.5 0.54 ± 2.0 39 15 34 ± 4.4 5.9 ± 11 6.3 ± 2.5 0.29 ± 7.8
H/R 69 16 17 ± 3.9 1.2 ± 6.7 3.8 ± 2.6 2.3 ± 2.3 68 23 38 ± 3.7 7.5 ± 9.1 12 ± 2.8 1.8 ± 2.6
R/R 64 20 24 ± 3.5 1.5 ± 8.1 6.2 ± 2.9 0.41 ± 2.9 36 21 24 ± 3.4 2.4 ± 9.8 9.5 ± 2.9 0.42 ± 2.3
p-value a   0.07 0.2 0.02 0.03 0.5   0.07 0.2 0.05 0.01 0.04
R-allele carriers 133 18 20 ± 3.7 1.3 ± 7.3 4.8 ± 2.8 0.43 ± 2.5 93 22 33 ± 3.6 5.0 ± 10 11 ± 2.8 0.5 ± 2.5
p-value b   0.3 0.4 0.007 0.8 0.2   0.03 0.08 0.1 0.009 0.4
H-allele carriers 104 22 17 ± 3.6 0.89 ± 6.7 3.9 ± 2.8 0.46 ± 2.3 107 20 37 ± 3.9 6.8 ± 9.5 9.4 ± 2.8 0.44 ± 4.4
p-value c   0.02 0.9 0.7 0.004 0.02   0.9 0.09 0.02 0.9 0.8
  1. The results are expressed in ELISA units and presented as geometric means ± SD.
  2. a Statistical analysis of differences in IgG subclass levels between the different genotypes tested with ANOVA
  3. b Statistical analysis of differences in IgG subclass levels between the R-allele carriers and HH homozygotes Mann-Whitney.
  4. c Statistical analysis of differences in IgG subclass levels between the H-allele carriers and RR homozygotes by Mann-Whitney.