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Table 3 Comparison of main outcome measures by study arm, Boromo Health District, Burkina Faso (2004–2006)

From: A community effectiveness trial of strategies promoting intermittent preventive treatment with sulphadoxine-pyrimethamine in pregnant women in rural Burkina Faso

 

Study arms

Comparisons

 

Intervention

    

Characteristic

A

B

Control

A vs. Control

B vs. Control

A vs. B

  

% (n/N)

  

OR (95%CI)

 

Antenatal care

      

≥ 3 ANC visits

62.3 (463/743)

42.3 (339/801)

45.8 (341/744)

1.95 (0.86–4.45)

0.87 (0.36–2.10)

2.25 (0.86–5.92)

1st ANC visit in third trimester †

18.7 (127/679)

28.5 (199/699)

30.8 (205/666)

0.52 (0.26–1.03)

0.90 (0.47–1.70)

0.58** (0.44–0.76)

≥ 2 doses IPT-SP

69.9 (519/743)

48.6 (389/801)

   

2.45* (1.25–4.82)

Home visit at 32 weeks

      

Anaemia (PCV < 33)

49.4 (288/583)

48.7 (285/585)

56.4 (299/530)

0.75 (0.37–1.54)

0.73 (0.36–1.50)

1.03 (0.68–1.56)

Moderate/severe anaemia (PCV < 30)

23.8 (139/583)

27.7 (162/585)

30.2 (160/530)

0.72 (0.39–1.34)

0.89 (0.45–1.73)

0.82 (0.62–1.08)

Peripheral parasitaemia

20.3 (121/597)

19.4 (120/618)

29.9 (167/558)

0.60* (0.39–0.91)

0.56** (0.40–0.80)

1.05 (0.67–1.67)

Delivery

      

Anaemia (PCV < 33) ‡

31.1 (137/440)

32.8 (131/399)

40.2 (150/373)

0.67 (0.38–1.18)

0.73 (0.39–1.36)

0.92 (0.51–1.69)

Moderate/severe anaemia (PCV < 30) ‡

16.8 (74/440)

16.8 (67/399)

19.8 (74/373)

0.82 (0.46–1.46)

0.82 (0.46–1.46)

1.00 (0.58–1.72)

Peripheral parasitaemia‡

17.4 (87/499)

20.1 (95/472)

33.3 (144/432)

0.42*** (0.30–0.60)

0.50** (0.37–0.69)

0.84 (0.60–1.18)

Placental parasitaemia

18.1 (89/491)

20.5 (90/440)

30.3 (131/432)

0.51** (0.37–0.70)

0.59* (0.44–0.78)

0.86 (0.58–1.29)

Low birth weight (< 2500 grams) §

16.2 (95/585)

18.6 (128/687)

22.3 (132/593)

0.68 (0.42–1.08)

0.80 (0.46–1.39)

0.85 (0.61–1.17)

Miscarriage/stillbirths ||

5.5 (41/742)

4.1 (33/801)

4.9 (36/742)

1.15 (0.89–1.48)

0.84 (0.55–1.28)

1.36 (0.88–2.12)

  1. Intervention A = IPTp+promotion; Intervention B = IPTp alone; Control = CQ chemoprophylaxis; ANC = antenatal care; PCV = packed cell volume; OR = odds ratio; CI = confidence interval.
  2. The non-adjusted risk estimates are presented as these did not change when adjusted for possible confounders.
  3. * p < 0.05; ** p < 0.01; *** p < 0.001;
  4. † singleton live-births only;
  5. ‡ only samples taken the day of delivery;
  6. § live born singletons weighed within 8 days after delivery;
  7. || 3 maternal deaths not included