| |
Study arms
|
Comparisons
|
|---|
| |
Intervention
| | | | |
|---|
|
Characteristic
|
A
|
B
|
Control
|
A vs. Control
|
B vs. Control
|
A vs. B
|
|---|
| | |
% (n/N)
| | |
OR (95%CI)
| |
|---|
|
Antenatal care
| | | | | | |
|
≥ 3 ANC visits
|
62.3 (463/743)
|
42.3 (339/801)
|
45.8 (341/744)
|
1.95 (0.86–4.45)
|
0.87 (0.36–2.10)
|
2.25 (0.86–5.92)
|
|
1st ANC visit in third trimester †
|
18.7 (127/679)
|
28.5 (199/699)
|
30.8 (205/666)
|
0.52 (0.26–1.03)
|
0.90 (0.47–1.70)
|
0.58** (0.44–0.76)
|
|
≥ 2 doses IPT-SP
|
69.9 (519/743)
|
48.6 (389/801)
| | | |
2.45* (1.25–4.82)
|
|
Home visit at 32 weeks
| | | | | | |
|
Anaemia (PCV < 33)
|
49.4 (288/583)
|
48.7 (285/585)
|
56.4 (299/530)
|
0.75 (0.37–1.54)
|
0.73 (0.36–1.50)
|
1.03 (0.68–1.56)
|
|
Moderate/severe anaemia (PCV < 30)
|
23.8 (139/583)
|
27.7 (162/585)
|
30.2 (160/530)
|
0.72 (0.39–1.34)
|
0.89 (0.45–1.73)
|
0.82 (0.62–1.08)
|
|
Peripheral parasitaemia
|
20.3 (121/597)
|
19.4 (120/618)
|
29.9 (167/558)
|
0.60* (0.39–0.91)
|
0.56** (0.40–0.80)
|
1.05 (0.67–1.67)
|
|
Delivery
| | | | | | |
|
Anaemia (PCV < 33) ‡
|
31.1 (137/440)
|
32.8 (131/399)
|
40.2 (150/373)
|
0.67 (0.38–1.18)
|
0.73 (0.39–1.36)
|
0.92 (0.51–1.69)
|
|
Moderate/severe anaemia (PCV < 30) ‡
|
16.8 (74/440)
|
16.8 (67/399)
|
19.8 (74/373)
|
0.82 (0.46–1.46)
|
0.82 (0.46–1.46)
|
1.00 (0.58–1.72)
|
|
Peripheral parasitaemia‡
|
17.4 (87/499)
|
20.1 (95/472)
|
33.3 (144/432)
|
0.42*** (0.30–0.60)
|
0.50** (0.37–0.69)
|
0.84 (0.60–1.18)
|
|
Placental parasitaemia
|
18.1 (89/491)
|
20.5 (90/440)
|
30.3 (131/432)
|
0.51** (0.37–0.70)
|
0.59* (0.44–0.78)
|
0.86 (0.58–1.29)
|
|
Low birth weight (< 2500 grams) §
|
16.2 (95/585)
|
18.6 (128/687)
|
22.3 (132/593)
|
0.68 (0.42–1.08)
|
0.80 (0.46–1.39)
|
0.85 (0.61–1.17)
|
|
Miscarriage/stillbirths ||
|
5.5 (41/742)
|
4.1 (33/801)
|
4.9 (36/742)
|
1.15 (0.89–1.48)
|
0.84 (0.55–1.28)
|
1.36 (0.88–2.12)
|
- Intervention A = IPTp+promotion; Intervention B = IPTp alone; Control = CQ chemoprophylaxis; ANC = antenatal care; PCV = packed cell volume; OR = odds ratio; CI = confidence interval.
- The non-adjusted risk estimates are presented as these did not change when adjusted for possible confounders.
- * p < 0.05; ** p < 0.01; *** p < 0.001;
- † singleton live-births only;
- ‡ only samples taken the day of delivery;
- § live born singletons weighed within 8 days after delivery;
- || 3 maternal deaths not included
