Table 1 Baseline characteristics of the study population having completed Day 7 follow-up (n = 93)
Patients' characteristics | All patients |
|---|---|
Male (n = 74) | 79.6% |
Age (in years)a | 26.6 (8.8) [13–53], 13.7 – 41.2 |
Weight (in kg)a | 50.7 (7.1) [30.0–70.0], 39.7 – 63.0 |
Tympanic temperature (in °C)a | 37.2 (1.1) [34.9–40.1], 35.8 – 39.0 |
Mixed infection, PF+PV (n = 16) | 17.2% |
Geometric mean parasite count per μl [range] | 7386 [79–190546] |
Total artesunate dose (in mg)b | 600 [300–825] |
Previous artesunate treatment (n = 26) | 28% |
Time of last artesunate treatment (in month)b | 4 [1 – 8] |
Tympanometry characteristics | |
Middle ear pressure, left ear (in daP)b | -15 [-145 – +25] |
Middle ear pressure, right ear (in daP)b | -15 [-140 – +95] |
Static compliance, left ear (in ml)b | 0.48 [0.16–3.08] |
Static compliance, right ear (in ml)b | 0.46 [0.15–2.52] |
Tympanometric gradient, left ear (dimensionless)a | 0.49 (0.15) [0.19–0.83], 0.22 – 0.77 |
Tympanometric gradient, right ear (dimensionless)a | 0.46 (0.15) [0.09–0.81], 0.23 – 0.74 |